If you're a startup working on a product for the healthcare industry, Boston is the place to be. During a trip to Bean Town, I was curious to hear what startup founders found most challenging in a city so rich with resources. The gripes I usually hear elsewhere, like troubles with seed funding or U.S. Food and Drug Administration regulation, didn't come up as much. Instead, these founders seemed to find the more personal elements of entrepreneurship most challenging. Many times I found myself talking to people who had made a shift from working in tech or research to becoming a business owner.